Pantheon SEMPARIS Le serveur des séminaires parisiens Paris

Status Confirmed
Seminar Series LPTMS
Subjects cond-mat.stat-mech
Date Tuesday 10 October 2023
Time 11:00
Institute LPTMS
Seminar Room Salle des séminaires du FAST et du LPTMS, bâtiment Pascal n°530
Speaker's Last Name Carbone
Speaker's First Name Alessandra
Speaker's Email Address
Speaker's Institution IBPS Sorbonne
Title The complexity of protein interactions
Abstract I will describe two facets of the interaction of proteins with other biological molecules. Firstly, I will define soft disordered (flexible, amorphous, or intrinsically disordered) regions in a protein with increasing numbers of bound interactors and analyze the correlation between disorder, interfaces and assembly. Secondly, I will address the question of reconstructing, ab initio, protein-protein interaction networks from protein language models and Neural Networks (NN) with memory from sequences with SENSE-PPI. SENSE-PPI addresses interactions between protein sequences, possibly intrinsically disordered, belonging to a model or non-model organism, or to different species such as human and viruses.
arXiv Preprint Number

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